Oxford boss Michael Appleton wants his side to make amends for the defeat to Oldham on Tuesday evening against Scunthorpe on Saturday.
The hosts are looking to bounce back from a 2-1 reverse in Lancashire, whilst Scunthorpe will be buoyant after a last gasp win over Rochdale at Glanford Park.
“Hopefully we can put in a performance that gets rid of the memories of Tuesday night,”Appleton told Oxford’s official website.
“Scunthorpe are going through a little bit of a tricky spell at the moment after being fantastic for five or six months of the season but it looks as though they have come through that now after Tuesday night.
“It is going to be a good test. I have said it plenty of times that we have progressed as a team this season and this will be another good gauge.”